We have great offers for daily, weekly and long term rentals in Santiago. Find the cheapest prices online, for your future Car Rental in Santiago in 4 quick easy steps. Book now at the lowest possible rates only with a small down payment and pay the rest when you pick up the car.

  • Customer benefits:
  • Quality & Expertise
  • Free amendments before rental start
  • Free cancellation up to 48h before rental
  • 24/7 customer service
  • Club Member Discount

Flexible Booking Process

No need for huge up-front costs. Search for the best deal for you in Santiago and book it with only a small advance payment, you will pay the remaining amount during the car pickup time.

Free Extras & Cancellation

In case your plans change you can cancel or do minor modifications for free up to 48 hours before your rental starts. We will also include all special offers in Santiago and surcharges from our partners on the final price.

Quality & Expertise

We constantly evaluate our partners in the level of service they provide in Santiago so we can ensure the quality of service you will receive.


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Why rent a car in Santiago?

Renting a car in Santiago, Panama, offers unparalleled flexibility to explore the city's rich cultural heritage and the surrounding natural attractions at your own pace. With a personal vehicle, you can easily visit historical sites, vibrant markets, and scenic landscapes that might be less accessible via public transportation.

Additionally, having a car allows you to embark on spontaneous day trips to nearby destinations, such as the pristine beaches of Santa Catalina or the lush trails of Parque Nacional Coiba, enhancing your travel experience with convenience and comfort.

Car rental tips for Santiago

  • Santiago serves as a convenient base for renting a car, offering a calmer environment compared to Panama City and immediate access to the countryside, making it ideal for travelers looking to explore the region's natural attractions.
  • When renting a car in Santiago, ensure you have a valid driver's license and be aware that some rental companies may require drivers to be at least 25 years old, with potential additional fees for younger drivers.
  • Be prepared for police stops and checkpoints, which are common in Panama. Always carry your rental agreement, driver's license, and passport to present when requested.
  • Before accepting the rental car, thoroughly inspect it for any existing damage and ensure that all such issues are documented in the rental agreement to avoid potential disputes upon return.

FAQs about renting a car in Santiago

What is the recommended car type/category?

A compact or mid-sized car is recommended for navigating Santiago's city streets and nearby attractions. If planning to explore rural areas or coastal regions like Santa Catalina, an SUV or vehicle with higher clearance may be beneficial for handling varied terrains.

What are the parking options?

Parking in Santiago is generally accessible, with options including street parking and designated parking lots near major attractions and shopping centers. It's advisable to use official parking areas to ensure vehicle safety.

What's the speed limit?

In Panama, the speed limit on highways is typically 100 km/h (62 mph), while city streets have limits ranging from 25 to 30 km/h (15 to 19 mph). Always pay attention to road signs, as limits can vary, especially in smaller towns and residential areas.

Popular attractions

  • St. James the Apostle Cathedral: A historic cathedral in Santiago de Veraguas, declared a historical monument in 2014, known for its beautiful architecture and significance in local religious festivities.
  • Escuela Normal Juan Demóstenes Arosemena: A historic school building dating back to 1938, showcasing Spanish colonial architecture and serving as a significant educational institution in the region.
  • Santiago Mall: A popular commercial center featuring a variety of shops, supermarkets, restaurants, banks, and entertainment options including cinemas and playgrounds.

More places to visit

  • Santa Catalina Beach: A tropical paradise offering some of the best surfing in Panama, with easy access to snorkeling, world-class diving at Parque Nacional Coiba, and superb fishing opportunities.
  • Parque Nacional Coiba: A world-famous protected natural marine reserve, perfect for bird watching and featuring a vast variety of marine life, making it a haven for nature enthusiasts.

Highly recommended by our customers

All Car Rental Brands in Santiago

Experience the difference with rentals from trusted brands. We focus on quality and customer satisfaction, so you can enjoy every mile of your journey.

National Car Rental

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Alamo Car Rental

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SIXT Car Rental

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Enterprise Car Rental

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Budget Car Rental

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Hertz Car Rental

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Europcar Car Rental

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Keddy Car Rental

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Thrifty Car Rental

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AVIS Car Rental

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Firefly Car Rental

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: This company has yet to receive any customer evaluations.

Find a car according to your needs


Small / Economy

You want a small, fuel-efficient vehicle for your trip? We provide a large range of options for you to select from. Save money while still getting a reliable vehicle!

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Hybrid / Electric

A hybrid car rental gives you the option to travel using different kinds of power, save energy, and cut down on emissions. Get where you need to go without constantly stopping for gas.

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Prestige Cars

Renting a luxury car gives you the chance to drive your dream car at an affordable price. This puts you in the driver’s seat of luxury cars from internationally renowned brands.

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Stationwagon / Minibus

You are on a family vacation or group outing? Our minibus and station wagons are perfect for the job. Minivans and 7-9 seaters are designed to provide a comfortable ride for everyone to enjoy.

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The cheapest car rental deals


*Displayed prices are the best daily rates found by our customers during the last two weeks. (Subject to change)

Website advantages

  • Destinations in almost every city in the world.
  • Competitive prices from trusted car rental brands
  • Genuine customer evaluation scores for each brand
  • Multilingual website

Customer benefits

  • Free amendments before rental start
  • Free cancellation up to 48h before rental
  • 24/7 customer service
  • Club Member Discount

One ways are supported! You want to pick up your car and return it to a different location, we can do it!

No hidden fees with us! Select your preferences and see the total prices before booking! Any extra fees that may apply because of driver's age or late pick up time selection, will always be included on the total price.

No need for full payment! Book your car with just a small amount and give the rest upon pick up.